UKB Somatic Browser
Find mutations and their links to proteins and diseases
Explore clonal hematopoiesis associations with proteins and disease in UK Biobank.
Search by mutated gene (e.g. DNMT3A) or protein (e.g. BCL2).
Variant Analysis
Single-variant level details, including VAFs and unadjusted age association
Frequency vs Mean Age
Variant Table
PheWAS Results
Explore mutation-phenotype associations, adjusted for age, smoking, and genetic ancestry.
Association Table
Effect Size Overview
Phenotype Distribution
PWAS Results
Explore mutation-protein associations, adjusted for age, smoking, cell type composition, and genetic ancestry.
Protein Associations
Volcano Plot
Effect Size Distribution
About the Weinstock Lab
Trying to understand how our DNA changes in our blood cells as we age.
The UKB Somatic Variation Browser is developed by the Weinstock Lab at Emory University's Department of Human Genetics.
Accompanying manuscript
Read more about this work in the preprint Genome-wide characterization of clonal hematopoiesis reveals extensive non-coding putative driver mutations .
Affiliations
We are members of the Winship Cancer Institute and the Center of Computational and Quantitative Genetics .
